“If you consider the first person who will reach the age
of 200, in approximately what year was he or she
born?”
The above question was posed by Daryl on the comment
thread of our recent Aubrey de Grey
article on life extension. Please vote and if you do be sure to
explain your reasoning in the comments section!
And for the sake of argument, let’s not include cryonics. So the
rules are that the person can not have already been dead. :)
This week, researchers from Canada and Scotland made a major advancement in the field of stem cell biology. They discovered a method to successfully reprogram somatic cells into stem cells without the use of viruses.
Induced pluripotent stem cells (iPSCs) are a type of stem cells derived from adult somatic cells by forcing expression of genes shown to sufficiently reprogram somatic cells into stem cells. iPSCs have been shown to possess key characteristics of embryonic stem cells (ESCs), the most important of which is the ability to give rise to cells of all three germ layers. iPSCs are an ideal source of stem cells because they circumvent the need for human embryos to generate stem cells. Additionally, because they can be generated from one’s own somatic cells which are readily available, iPSCs can be used for patient-specific therapies, thereby reducing the risk of immune rejection.
Scientists in this revolution are focusing on actually curing
health problems, not just treating them. Their goals include
developing therapies to completely eradicate diseases like cancer,
diabetes, heart attacks, strokes, osteoporosis, arthritis, and
spinal cord injuries. Virtually any disease that results from
damaged or failing tissues can be targeted for elimination with
regenerative medicine.
Derived from biology, biochemistry, physics, engineering, and
other fields, this medical revolution will utilize stem cell
therapies, genetic engineering, and nanotech to repair tissues and
organs inside the body, and build new body parts in the lab when
necessary. Given cohesive government initiative and adequate
funding, the report states that progress could be realized in the
following timeline:
2010-2015 – Develop multiple applications for skin, cartilage,
bone, blood vessel, and some urological products; enable insurance
companies to cover these procedures; establish FDA standards for newly-developing technologies; make
available cell banks for unlimited tissue storage; and allow
researchers access to materials they need to design new therapies
and create cost-effective production methods. (cont.)
An honest assessment of my exposure to the extreme life-extension meme.
Since being exposed to the idea of extreme life extension, which admittedly was only several months ago, I’ve found myself reacting in a more skeptical and reactionary manner than I often do when confronted with other radical new futuristic ideas and technologies. When I read about possibilities of faster than light travel, I get excited. Predictions of nano-assemblers make me hopeful. I find designs for colonies on the Moon and Mars fascinating. But when I read about trends in regenerative medicine and nanotechnology that some experts believe will conquer death, I am not enthusiastic. Instead I become very skeptical, nervous and even angry. On one level, I am surprised that I could be anything other than overjoyed that ending death could be a possibility, I very much enjoy life and, as a living organism, I have a strong instinct to stay alive. Yet I find it extremely difficult to wrap my head around the idea of life without death.
So why does extreme life extension make me uncomfortable? I’m not, nor have I ever been a religious person, though I have respect for those who are. I was raised by two atheists with PhDs in science and I haven’t ever held out hope for an afterlife. It’s not that I don’t value human life – I value it very much. As a humanist, I believe very strongly that each human life is sacred and unique and believe it is within our power, and is indeed our responsibility, to work towards giving every person as good a life as possible. I also don’t believe I am a Luddite. I am increasingly excited about technology in general, I love my cellphone and the new snazzier one I will someday get. I love my computer and wonders of the Internet. I’m fascinated by the promise of the Semantic Web. I also embrace any technology that could cure diseases or repair injuries. But when it comes to anything that may fundamentally change the way I am or the way people are in general, I am very hesitant.
I thought it would be interesting to explore some of the reactions, thoughts and feelings I have when pondering extreme life extension, as I think they probably overlap with those of the people who have been or will be exposed to these ideas.
The logic problem: Defying death seems to break down logic
When I think about the end of death, I find it hard to express myself in logical, objective terms. I am tempted to call my reactions
against extreme life extension a “bias” because there is undoubtedly an emotional aspect and I do have a predisposition against the idea. But “bias” implies an illogical perspective – can considering death a certainty really be regarded as illogical? I begin to think, “Hasn’t everything that has ever lived also died?” Well, yes, except of course for the trillions of life forms that are alive right now. So the answer becomes not “Everything that has ever lived has died.” but “Everything that has ever died, has died.” This answer is so logically recursive that it isn’t even that useful.